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Storage and Handling Instructions For GLP-1 Medicines

How to store, refrigerate, travel with, and handle GLP-1 medication safely.

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Quick Rules

  • Keep compounded vials refrigerated at 36 to 46°F (2 to 8°C). Do not freeze. Keep away from heat and sunlight.

  • Store in the original carton or amber vial to protect from light.

  • Inspect before each use. Solution should be clear and colorless to slightly yellow. Do not use if cloudy, discolored, or has particles.

  • Use a new sterile needle and syringe every time. Never share vials or needles. Dispose of sharps in an FDA‑cleared container.

How to Store Your Compounded GLP‑1 Vial

Compounded semaglutide and tirzepatide are sterile, multi‑dose vials. At home, keep them in the refrigerator between 36 and 46°F (2 to 8°C). Do not place vials near freezer vents, do not freeze, and avoid direct sunlight or hot cars. These temperature and light precautions are consistent with GLP‑1 labeling and help maintain potency.

Keep vials in their original carton or an amber container to limit light exposure. Return the vial to the fridge immediately after each dose.

Safe Handling to Prevent Contamination and Errors

Before each draw, clean the rubber stopper with an alcohol swab and let it dry. Use a brand‑new sterile syringe and needle for every injection. Write the date you first punctured the vial on the label. These simple steps lower the risk of contaminating multi‑dose vials.

Draw up doses exactly as instructed by your clinician. Compounded vials come in different concentrations, and dosing errors have been reported when patients guess or convert units on their own. If the numbers on your syringe or the concentration on your label do not match the plan you were given, stop and contact us.

Put used needles immediately in an FDA‑cleared sharps container. If you do not have one, use a heavy‑duty plastic household container with a tight, puncture‑resistant lid until you can obtain a proper sharps container. Follow local rules for disposal.

Multi-Dose Vial Safety (What is the 28-day puncture rule?)

While manufacturers typically test multi-dose vials for sterility up to 28 days, pharmacies can extend this timeframe based on their own rigorous safety testing for specific medications. When you receive a multi-month supply in one vial, the pharmacy has verified it remains safe and effective for the entire treatment period.

Travel and Temperature Excursions

When you travel, carry vials in your hand luggage with gel ice packs to keep them cold but not frozen. TSA allows medically necessary liquids, medications, needles, and gel ice packs in carry‑on bags. Tell officers you are carrying medication and separate it for screening.

If a vial was left unrefrigerated or exposed to heat, do not assume it is safe. Contact us or your pharmacy to review the exact exposure against your product’s storage limits. Protecting from freezing, heat, and light is essential for peptide stability.

When to Contact Us

  • You see cloudiness, discoloration, or particles.

  • The vial was frozen, left in a hot car, or sat out of the fridge and you are unsure how long.

  • The label is damaged, or the concentration does not match your instructions.

  • You need a travel letter, sharps container, or replacement supplies.


Need help now?

You can reach us anytime through the Messenger widget in the bottom-left corner or by emailing [email protected].

Our patient care team will verify your compounded GLP-1 storage plan, confirm dosing, and make sure your GLP‑1 vial handling is safe and simple.

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